New CRISPR Technique Speeds Up Genetic Editing

If genetic editing wasn’t impressive enough already, a recent breakthrough in CRISPR technology has accelerated the quest towards editing entire gene networks in a single step. While this finding will probably shorten the time frames required for finding cures for deadly illnesses, it can also bring humanity closer to threats of bioterrorism.

The new technique

Prior to this finding, the process could only target a single gene for editing purposes, but now the ETH scientists managed to target 25 at once and they speculate that theoretically speaking, this method could target hundreds. Here is the official description of the process:

“ We demonstrate that both Cas12a and a clustered regularly interspaced short palindromic repeat (CRISPR) array can be encoded in a single transcript by adding a stabilizer tertiary RNA structure. By leveraging this system, we illustrate constitutive, conditional, inducible, orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs delivered on a single plasmid. Our method provides a powerful platform to investigate and orchestrate the sophisticated genetic programs underlying complex cell behaviors. “

While this new method only boosts the efficiency of CRISPR, time plays a vital role in genetic editing. Complex genetic conditions occur by the interaction of genes in a cell. Targeting each gene individually to test a different setup usually takes a great period of time and the process might require intensive repetition in order to reveal the desired genetic variation, therefore reducing the time required to produce each generation makes the discovery and research process a lot more efficient. This might lead to inventing more important gene therapies which could potentially cure morbid conditions which have a high number of daily death tolls.

About the Author: Jose Brewer

As the leading voice behind, I'm Jose Brewer, a tech enthusiast and seasoned writer, passionate about unraveling the complexities of the latest technology for my readers. My journey in the tech world began with a Bachelor's degree in Computer Science, which opened the doors to a dynamic career in software development. This hands-on experience in the tech industry has been the cornerstone of my writing, allowing me to bring a rich depth of knowledge to my articles.

Leave a Reply

Your email address will not be published. Required fields are marked *

How to whitelist website on AdBlocker?

How to whitelist website on AdBlocker?

  1. 1 Click on the AdBlock Plus icon on the top right corner of your browser
  2. 2 Click on "Enabled on this site" from the AdBlock Plus option
  3. 3 Refresh the page and start browsing the site